The 2019 SCOR Young European Researcher Prize for Research into Alzheimer’s disease was awarded to Dr Federica Agosta, medical doctor and researcher at the San Raffaele Hospital in Milan. Using MRI (magnetic resonance imaging) techniques, her work aims to identify functional and structural markers of degeneration to enable early diagnosis of Alzheimer’s and related disorders. She is also particularly interested in young-onset Alzheimer’s disease. She has published more than 200 articles in specialist scientific journals. The jury of renowned European researchers was chaired by Professor Jean-François Dartigues of the Bordeaux Population Health Research Center.

Commenting on the award, André Levy-Lang, Chairman of the SCOR Foundation for Science, said: “Advances in Alzheimer’s disease research, which the SCOR Foundation has supported for many years, play a key role in managing the risks faced by older age groups. Dr Agosta’s research is helping more specifically to pursue the age-old goal of prolonging life expectancy.”

Federica Agosta on the French Alzheimer’s Research Foundation (Fondation Recherche Alzheimer) website.

Publications by Federica Agosta:

• Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias.
  Chételat G, Arbizu J, Barthel H, Garibotto V, Law I, Morbelli S, van de Giessen E, Agosta F, Barkhof F, Brooks DJ, Carrillo MC, Dubois B, Fjell AM, Frisoni GB, Hansson O, Herholz K, Hutton BF, Jack CR Jr, Lammertsma AA, Landau SM, Minoshima S, Nobili F, Nordberg A, Ossenkoppele R, Oyen WJG, Perani D, Rabinovici GD, Scheltens P, Villemagne VL, Zetterberg H, Drzezga A. Lancet Neurol.
  2020 Nov;19(11):951-962. doi: 10.1016/S1474-4422(20)30314-8. PMID: 33098804 Review.
• MRI of Motor and Nonmotor Therapy-Induced Complications in Parkinson's Disease.
  Donzuso G, Agosta F, Canu E, Filippi M. Mov Disord.
  2020 May;35(5):724-740. doi: 10.1002/mds.28025. Epub 2020 Mar 17. PMID: 32181946 Review
• Deep learning: a turning point in acute neurology.
  Filippi M, Cividini C, Agosta F. Lancet Digit Health. 2020 Jun;2(6):e273-e274. doi: 10.1016/S2589-7500(20)30106-0. Epub
  2020 May 14. PMID: 33328119 No abstract available
• Functional brain connectome in posterior cortical atrophy.
  Migliaccio R, Agosta F, Basaia S, Cividini C, Habert MO, Kas A, Montembeault M, Filippi M. Neuroimage Clin.
  2020;25:102100. doi: 10.1016/j.nicl.2019.102100. Epub 2019 Nov 20. PMID: 31865020 Free PMC article
• Focus on the heterogeneity of amyotrophic lateral sclerosis.
  Bendotti C, Bonetto V, Pupillo E, Logroscino G, Al-Chalabi A, Lunetta C, Riva N, Mora G, Lauria G, Weishaupt JH, Agosta F, Malaspina A, Basso M, Greensmith L, Van Den Bosch L, Ratti A, Corbo M, Hardiman O, Chiò A, Silani V, Beghi E. Amyotroph Lateral Scler Frontotemporal Degener.
  2020 Nov;21(7-8):485-495. doi: 10.1080/21678421.2020.1779298. Epub 2020 Jun 25. PMID: 32583689
• Amyloid-Related Imaging Abnormalities and β-Amyloid-Targeting Antibodies: A Systematic Review.
  Filippi M, Cecchetti G, Spinelli EG, Vezzulli P, Falini A, Agosta F.
  JAMA Neurol. 2022 Mar 1;79(3):291-304. doi: 10.1001/jamaneurol.2021.5205. PMID: 35099507 Review.
• Automated classification of Alzheimer's disease and mild cognitive impairment using a single MRI and deep neural networks.
  Basaia S, Agosta F, Wagner L, Canu E, Magnani G, Santangelo R, Filippi M; Alzheimer's Disease Neuroimaging Initiative.
  Neuroimage Clin. 2019;21:101645. doi: 10.1016/j.nicl.2018.101645. Epub 2018 Dec 18. PMID: 30584016
• MRI of non-Alzheimer's dementia: current and emerging knowledge.
  Filippi M, Agosta F.
  Curr Opin Neurol. 2018 Aug;31(4):405-414. doi: 10.1097/WCO.0000000000000571. PMID: 29746400 Review.
• Perspectives and challenges in patient stratification in Alzheimer's disease.
  Abdelnour C, Agosta F, Bozzali M, Fougère B, Iwata A, Nilforooshan R, Takada LT, Viñuela F, Traber M.
  Alzheimers Res Ther. 2022 Aug 13;14(1):112. doi: 10.1186/s13195-022-01055-y. PMID: 35964143
• Natural Speech Analysis: A Window Into Alzheimer Disease Phenotypes.
  Agosta F, Filippi M.
  Neurology. 2022 Jul 26;99(4):137-138. doi: 10.1212/WNL.0000000000200843. Epub 2022 May 4. PMID: 35508400

More publications by Federica Agosta are available on the National Library of Medicine website.